D3K2: A Powerful Combo Enhanced with Nanotechnology

Written By Solex LLC

Do you live in an area that is often cloudy? Do you have a job where you must be inside most of the day? Do you adhere to a strict vegan diet or have dairy allergies? If any of these sound like you, have you tried increasing your vitamin D3 supplementation?

Research shows that Vitamin D3 deficiency affects nearly 50% of the global population regardless of ethnicity or age [1]. Although Vitamin D3 is best known for promoting healthy bones and teeth, missing out on the "sunshine vitamin" has consequences beyond bone health.

Vitamin D3 plays multiple daily roles in the body, which include creating and maintaining healthy tissues, preventing chronic diseases, reducing inflammation, promoting immune function, and aiding cognitive support. That's only the beginning [2, 3, 4].

To take these benefits a step further, research shows Vitamin D3 and Vitamin K2 have a synergistic relationship that ensures the calcium transported by Vitamin D3 is absorbed where needed rather than accumulating in deposits in the arteries [5, 6, 7].

Vitamin K2 has also been found to build healthy bones, improve heart health, and aid in blood clotting.

Solex has created a unique formula of D3K2, using nanotechnology, to promote these and many more benefits. The ingredients in our Proprietary Blend take this formulation to the next level by supporting and enhancing all that Vitamin D3 and K2 offers.

Whether inadequate sunlight exposure or the lack of vitamin D in foods prevents you from being Vitamin D sufficient, let D3K2 optimize your body to be the best it can be!

 

D3K2 Benefits

D3K2 is a high-potency formulation that goes beyond what other Vitamin D3 and Vitamin K2 supplements can provide. This precise combination perfectly supports the following benefits:

  • Inflammation management*

  • Bone and heart health benefits*

  • Cognitive support*

  • Immune system support*

  • Calcium metabolism regulation*

 

Ingredients and Serving Size Recommendation

  • Vitamin D3 (Cholecalciferol): D3 creates and maintains healthy tissues, prevents chronic diseases, reduces inflammation, promotes immune function, and aids cognitive support.

  • Vitamin E (D-Alpha-tocopherol): Acts as a powerful antioxidant in the body, promotes skin health, helps maintain cognitive decline, and improves immune function and lung function [8, 9, 10, 11].

Proprietary Blend:

  • Vitamin K2 (MK 7 Menaquinone): A powerful nutrient that plays an essential role in many aspects of your health. Research shows that K2 has beneficial effects in osteoporosis, cardiovascular disease, inflammation, Alzheimer’s disease, diabetes, and peripheral neuropathy {12, 13]

  • Vitamin K1 (Phylloquinone-4): An essential vitamin primarily transported and used by the liver, which helps to make various proteins that are needed for blood clotting and the building of bones [14, 15].

  • Astaxanthin (Haematococcus pluvialis extract): Works as a powerful antioxidant protecting cells from free radicals and oxidative stress, supports the immune system, acts on ROS to reduce proteins that can cause inflammatory diseases, promotes cognitive and heart health [16, 17, 18].

  • Vitamin K2 (MK 4 Menaquinone): The most active form of K2 [19]. Makes up 98% of the total vitamin K in the brain, reduces the proliferation of rheumatoid synovial cells in rheumatoid arthritis, preserves vascular smooth muscle cells, and transports nutrients into the body effectively among many other benefits. [20, 21, 22, 23}

Other Ingredients: Distilled water, Glycerine, Medium Chain Triglycerides, Erythritol, Phosphatidylcholine, Natural Flavor, Gum Arabic, Lemon oil, Xanthan Gum, Potassium Sorbate, Limonene.


Servings: 60

Serving Size: Spray 20 ml (approximately 20 pumps) daily. 1 m (10 pumps) in the morning and 1ml (10 pumps at night)

When spraying into the mouth, spray aiming toward the throat. (This product is for oral use only).

 

Nanotechnology in D3K2

Why is D3K2 the unique Vitamin D supplement in the market?

The secret is in Nanotechnology.

Nano comes from a ‘nanometer’ (1 billionth of a meter). To put it in perspective, take a round marble that is commonly used to play games and compare that to the size of the world.

Nano Technology separates the binding of molecular structures into smaller and smaller sizes to allow for more effective and efficient absorption. When this happens with molecular structures we consume in our supplements, they become bioavailable at the cellular level.

Nanosizing benefits in D3K2:

  • Massive absorption

  • Less waste

  • Lower biological stress

  • Lowers energy lost

 

Science and FAQs

  • Question: Who Can Benefit from Vitamin D3K2?

    • Middle-aged and Elderly Individuals

    • Post-Menopausal Women

    • Anyone with Low Vitamin D Status

    Question: Can I take D3K2 along with other supplements?

    • Yes! D3K2 can be used along with other supplements. Supplements like Pulse and Prime for Solex are perfect pairs for D3K2.

    Question: Why does the color of Vitamin D3K2 change from batch to batch?

    Answer: Due to the naturally sourced ingredients in the Vitamin D3K2 formula, color may change from batch to batch. Time of harvest, season, soil richness, temperature, light, and humidity and other environmental factors can impact plant based and naturally sourced ingredients. The following tests have been used to ensure that every batch has the highest level of quality and consistency to help you experience the anticipated benefits: Organoleptic testing, Microbial testing, Gas chromatography, Mass Spectrometry, Fourier-transform Infrared spectroscopy, Chirality testing, Isotopic testing and Heavy Metal testing.

  • Intro

    1. Forrest KY, Stuhldreher WL. Prevalence and correlates of vitamin D deficiency in US adults. Nutr Res. 2011 Jan;31(1):48-54. doi: 10.1016/j.nutres.2010.12.001. PMID: 21310306.

      https://pubmed.ncbi.nlm.nih.gov/21310306/

    2. “Office of Dietary Supplements - Vitamin D.” NIH Office of Dietary Supplements, U.S. Department of Health and Human Services.

      https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/#:~:text=Together%20with%20calcium%2C%20vitamin%20D,metabolism%20%5B1%2D3%5D.

    3. Saponaro F, Marcocci C, Zucchi R. Vitamin D status and cardiovascular outcome. J Endocrinol Invest. 2019 Nov;42(11):1285-1290. doi: 10.1007/s40618-019-01057-y. Epub 2019 Jun 6. PMID: 31172459.

      https://pubmed.ncbi.nlm.nih.gov/31172459/

    4. Martens, Pieter-Jan et al. “Vitamin D's Effect on Immune Function.” Nutrients vol. 12,5 1248. 28 Apr. 2020, doi:10.3390/nu12051248

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281985/

    5. van Ballegooijen, Adriana J et al. “The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review.” International journal of endocrinology vol. 2017 (2017): 7454376. doi:10.1155/2017/7454376

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613455/

    6. Hauschka PV. Osteocalcin: the vitamin K-dependent Ca2+-binding protein of bone matrix. Haemostasis. 1986;16(3-4):258-72. doi: 10.1159/000215298. PMID: 3530901.

      https://pubmed.ncbi.nlm.nih.gov/3530901/

    7. Theuwissen E, Smit E, Vermeer C. The role of vitamin K in soft-tissue calcification. Adv Nutr. 2012 Mar 1;3(2):166-73. doi: 10.3945/an.111.001628. PMID: 22516724; PMCID: PMC3648717.

      https://pubmed.ncbi.nlm.nih.gov/22516724/

      Vitamin D3 (Cholecalciferol)

    8. Aghadavod E, Soleimani A, Hamidi G, Keneshlou F, Heidari A, Asemi Z. Effects of High-dose Vitamin E Supplementation on Markers of Cardiometabolic Risk and Oxidative Stress in Patients with Diabetic Nephropathy: a Randomized Double-blinded Controlled Trial. Iran J Kidney Dis. 2018 May;12(3):156-162. PMID: 29891745.

      https://pubmed.ncbi.nlm.nih.gov/29891745/

    9. Teo CWL, Tay SHY, Tey HL, Ung YW, Yap WN. Vitamin E in Atopic Dermatitis: From Preclinical to Clinical Studies. Dermatology. 2021;237(4):553-564. doi: 10.1159/000510653. Epub 2020 Oct 16. PMID: 33070130.

      https://pubmed.ncbi.nlm.nih.gov/33070130/

    10. Lakhan, Ram et al. “The Role of Vitamin E in Slowing Down Mild Cognitive Impairment: A Narrative Review.” Healthcare (Basel, Switzerland) vol. 9,11 1573. 18 Nov. 2021, doi:10.3390/healthcare9111573

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8625211/

    11. Ghaffari J, Farid Hossiani R, Khalilian A, Nahanmoghadam N, Salehifar E, Rafatpanah H. Vitamin e supplementation, lung functions and clinical manifestations in children with moderate asthma: a randomized double blind placebo- controlled trial. Iran J Allergy Asthma Immunol. 2014 Apr;13(2):98-103. PMID: 24338254.

      https://pubmed.ncbi.nlm.nih.gov/24338254/

      Vitamin K2 (MK 7 Menaquinone)

    12. Jadhav, Nikita et al. “Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities.” Frontiers in pharmacology vol. 13 896920. 14 Jun. 2022, doi:10.3389/fphar.2022.896920

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237441/#:~:text=Vitamin%20K2%2D7%2C%20also%20known,disease%2C%20diabetes%20and%20peripheral%20neuropathy

    13. Schwalfenberg, Gerry Kurt. “Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health.” Journal of nutrition and metabolism vol. 2017 (2017): 6254836. doi:10.1155/2017/6254836

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494092/

      Vitamin K1 (Phylloquinone-4)

    14. Pearson, Keith. “Vitamin K1 vs K2: What’s the Difference?” Healthline, Healthline Media, 15 Sept. 2017.

      https://www.healthline.com/nutrition/vitamin-k1-vs-k2#TOC_TITLE_HDR_3

    15. Halder, Maurice et al. “Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease.” International journal of molecular sciences vol. 20,4 896. 19 Feb. 2019, doi:10.3390/ijms20040896

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413124/

      Astaxanthin (Haematococcus pluvialis extract)

    16. Bjørklund, Geir et al. “The Role of Astaxanthin as a Nutraceutical in Health and Age-Related Conditions.” Molecules (Basel, Switzerland) vol. 27,21 7167. 23 Oct. 2022, doi:10.3390/molecules27217167

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9655540/

    17. Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S. Functions of natural killer cells. Nat Immunol. 2008 May;9(5):503-10. doi: 10.1038/ni1582. PMID: 18425107.

      https://pubmed.ncbi.nlm.nih.gov/18425107/#:~:text=Natural%20killer%20(NK)%20cells%20are,spread%20and%20subsequent%20tissue%20damage

    18. WebMD Editorial Contributors. (2022, November 9). Astaxanthin: Health benefits, safety information, dosage, and more. WebMD.

      https://www.webmd.com/diet/health-benefits-astaxanthin

      Vitamin K2 (MK 4 Menaquinone)

    19. Koitaya N, Sekiguchi M, Tousen Y, Nishide Y, Morita A, Yamauchi J, Gando Y, Miyachi M, Aoki M, Komatsu M, Watanabe F, Morishita K, Ishimi Y. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women. J Bone Miner Metab. 2014 Mar;32(2):142-50. doi: 10.1007/s00774-013-0472-7. Epub 2013 May 24. PMID: 23702931.

      https://pubmed.ncbi.nlm.nih.gov/23702931/

    20. Zhang, Yuyi et al. “Association between vitamin K intake and depressive symptoms in US adults: Data from the National Health and Nutrition Examination Survey (NHANES) 2013-2018.” Frontiers in nutrition vol. 10 1102109. 22 Mar. 2023, doi:10.3389/fnut.2023.1102109

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073415/#:~:text=Vitamin%20K%20is%20present%20predominantly,synthesized%20by%20bacteria%20(24).

    21. “Choosing the Right Vitamin K2: Menaquinone-4 vs Menaquinone-7.” Natural Medicine Journal, 20 Apr. 2022.

      www.naturalmedicinejournal.com/journal/choosing-right-vitamin-k2-menaquinone-4-vs-menaquinone-7.

    22. Mandatori, Domitilla, et al. “Osteogenic Transdifferentiation of Vascular Smooth Muscle Cells Isolated from Spontaneously Hypertensive Rats and Potential Menaquinone-4 Inhibiting Effect.” Onlinelibrary, Journal of Cellular Physiology, 1 Apr. 2019.

      https://onlinelibrary.wiley.com/doi/epdf/10.1002/jcp.28576#

    23. Shade, Christopher W. “Liposomes as Advanced Delivery Systems for Nutraceuticals.” Integrative medicine (Encinitas, Calif.) vol. 15,1 (2016): 33-6.

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818067/

 

D3K2 and Pulse

Ready to take the benefits of D3K2 to the next level?

Pulse opens the vascular system by expanding and elasticizing arteries and veins, allowing more oxygen and D3K2 nutrient-rich blood to drive deeper and more effectively into the areas that need it most.

Pulse Benefits:  

  • Fight inflammation*

  • Better brain function*

  • Supports healthy blood pressure levels*

  • Antifatigue*

  • Helps with skin health*

  • Improves nutrient and oxygen to cells*

 

  • *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    If you are under the age of 18, or have a pre-existing medical condition, consult with your healthcare provider before taking this product.

    If you are pregnant or nursing, do not take this product.

    Discontinue use and consult your healthcare provider if any adverse reaction occurs. Do not use if the tamper-evident seal is broken. Keep out of reach of children.

Solex LLC
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