THINKdrops™: Enhanced Absorption With Liposomal Nanotechnology

A healthy brain is just as important as a healthy body when pursuing health and longevity.

The brain is the agent for all human actions and experiences as a species, producing our every thought, action, memory, feeling, and all bodily functions. 

Compared to other organs, the brain uses the highest amount of oxygen to generate energy to support its intensive neuronal activity [1]. Although this is good for energy consumption, high oxygen levels, and lipid-rich content may cause detrimental lagging and latent effects on the brain, creating a highly susceptible environment to oxidative stress [2]

Think™ was developed to improve brain and memory function by reducing oxidative damage and inflammation that cause age-related brain decline and neurodegenerative diseases. However, committed to offering the absolute best supplements, Solex saw an opportunity to make the best brain supplement even better. 

With new delivery forms available to enhance nutrient absorption, we made Think™ into a liposomal nanotechnology form to take the benefits of Think™ to the next level. 

Everything you love about Think™ is still part of the new THINKdrops™ formula, only now, with improved nutrient bioavailability. 

 

THINKdrops™ Benefits

  • Boost cognitive function*

  • Aid in mental processing*

  • Promote focus*

  • Optimize memory*

  • Sharpen mental clarity*

  • Optimize brain health throughout the aging process*

  • Decrease mental fatigue and brain fog*

  • Boost concentration*

  • NRF2 support*

 

Ingredients in THINKdrops™

The ingredients in THINKdrops™ work synergistically to improve brain function and reduce age-related decline in brain function.

Turmeric Extract (95% Curcuminoids) 40 mg:

Turmeric comes from the root of the Curcuma Longa plant. Turmeric contains medicinal properties called curcuminoids, the most important being Curcumin [3]. Curcumin is an anti-inflammatory compound that can increase the body’s antioxidant capacity, boost brain-derived neurotrophic factors (BDNF), and aid in mood and cognitive disorders [4, 5].

Proprietary Blend (27.75 mg):

  • Lion’s Mane Mushroom

    Lion’s Mane Mushroom (LM) has been shown to assist in repairing nerve damage and early gene expression in regeneration [6]. Lion’s Mane Mushroom significantly improves depressive disorder by modulating the serotonin, dopamine, norepinephrine, epinephrine, and histamine neurotransmitter systems in the brain and anti-inflammatory pathways [7].

  • Niacinamide

    Niacinamide (vitamin B3), an inhibitor of histone deacetylase, increased histone acetylation and enhanced memory in a mouse model of Alzheimer’s disease (AD) [8]. Supplementation with nicotinamide preserved mitochondrial function, and reduced accumulation of amyloid beta-peptides (a recognized critical initiator that triggers the progression of AD via accumulation and aggregation) and phosphorylation of tau protein (which led to neurofibrillary degeneration – a tangling of the fibril) in a mouse model of AD [9]. Niacinamide also protected beta-amyloid peptides-induced neurodegeneration by reducing oxidative stress and improving mitochondrial function [10]. Nicotinamide reduced glutamate-induced toxicity, and preserved NAD to support SIRT1 (silent information regulator 1) activity [11].

  • Phosphatidylserine

    Phosphatidylserine (PS) is needed for normal function of nerve cells and myelin sheath. Structural decline in PS levels in the cell membrane leads to impairment of neurotransmission in older individuals. Supplementation with PS prevented structural deterioration of membranes during aging, according to a meta-analysis review of 127 articles [12]. Phosphatidylserine is absorbed efficiently and crosses the blood-brain barrier easily. In addition, PS is also linked to improvement in the memory of Alzheimer’s disease patients, older individuals with memory problems, and attention deficit disorders in children [13]. Docosahexaenoic acid (DHA), a component of omega-3 fatty acids, improved the neuroprotective action of PS in the brain and oxidative stress [14].

  • Rhodiola Rosea

    Studies have shown that taking Rhodiola Rosea (RR) improves learning and function. Rhodiola Rosea can improve learning and memory function through antioxidant, cholinergic regulation (which is long-term memory consolidation), anti-apoptosis activities (proper molecular steps that lead to cell death – essentially, supporting the correct process to retire cells that have maximized their life and contribution within the brain), fight inflammation, improve coronary blood flow, and cerebral metabolism [15]

  • Co-Enzyme Q10

    Several studies focused on Co-Enzyme Q10 (CoQ10) show that mitochondrial dysfunctions are associated with neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) [16]. Mitochondrial dysfunction releases free radicals and cell death-causing proteins, all of which contribute to the death of nerve cells. CoQ10 is required by the mitochondria for generating energy in the cell and for cell function [17]

    CoQ10 decreases with age; thus, we can readily associate many brain function challenges with aging [18]. THINKdrops™ is designed with mitochondrial strengthening amounts of CoQ10 to further support and assist in improving the energy-producing ability of the mitochondria. A co-sponsored study between several Neurochemistry, Neurology centers, hospitals, and Harvard Medical School shows strong support for oral supplementation of CoQ10 to impact antioxidant protection, damage correction, and improved functioning [lbid].

  • Trans-Resveratrol

    Trans-resveratrol is the active ingredient in resveratrol. Studies suggest trans-resveratrol has a neuroprotective role in reducing neuroinflammation and certain levels of Alzheimer’s Disease [19].

Other Ingredients: distilled water, glycerine, MCT oil, cacao powder, erythritol, phosphatidylcholine, honey, gum arabic, xanthan gum, potassium sorbate, limonene.

 

Serving Size Recommendation

Dosage: 1ml per serving (60 servings per bottle). The serving size is approximately ten sprays: five in the morning and five at night. 

The fine spray of the bottle is used to mist the mouth with the nano ingredients from THINKdrops™. This misting will assist in spreading the benefits over the surface of the mouth and tongue to have the fastest absorption.

The bottle's pump must be "primed" for initial use (getting fluid into the straw). When needed, reset the pump by pulling the pump to full extension to repeat full sprays. Additionally, it's important to shake the bottle well before pumping so particles remain suspended evenly throughout the bottle.

 

Nanotechnology in THINKdrops™

Wondering why THINKdrops™ has lower dosages of ingredients than the average brain supplement?

The secret is in nanotechnology.

Nanotechnology separates the binding of molecular structures into smaller and smaller sizes to allow for more effective and efficient absorption. When this happens with the molecular structures we consume in our supplements, they become bioavailable at the cellular level, improving the reach of the ingredients without adding stress to the body.

Nanosizing benefits in THINKdrops™:

  • Enhanced absorption

  • Less waste

  • Lower biological stress

  • Lower energy lost

 

Science and FAQs

  • Q: Why is THINKdrops™ in spray form?

    A: The fine spray is to mist the mouth with the nano ingredients in THINKdrops™. This misting will assist in spreading the benefits over the surface of the mouth and tongue to have the fastest absorption.

    Q: How does the pump on the bottle work?

    A: The pump must be "primed" for initial use (getting fluid into the straw) for the fine spray pump used for Sleep.

    When needed, reset the pump by pulling the pump to full extension to repeat full sprays. Additionally, it's important to shake the bottle well before pumping so particles remain suspended evenly throughout the bottle.

    Q: Will Think™ capsules still be available?

    A: Yes! Think™ capsules will remain available in your back office. If you prefer supplements in capsule form, keep using Think.

    Q: Can I take THINKdrops™ daily?

    A: Yes, THINKdrops™ contains nanotechnology which allows a potent lower dose that will help your brain get the nutrients it needs to perform its best.

    Q: What are the active ingredients in THINKdrops™?

    A: Turmeric Extract (95% Curcuminoids) 40 mg, Proprietary Blend (27.75 mg): Lion’s Mane Mushroom, Niacinamide, Phosphatidylserine, Rhodiola Rosea, Co Enzyme Q10, Trans-Resveratrol.

    Q: What is the difference between THINKdrops™ and THINKdrops™ with Krill?

    A: The only difference is Krill has been added to THINKdrops™ with Krill. Regular THINKdrops™ does not include Krill in its formulation.

    Krill is a shellfish that provides EPA and DHA, and astaxanthin, which contributes multiple cognitive and vascular health benefits. The taste of Krill can taste oceanic or fishy. If you are sensitive to the taste, add it to your favorite beverage.

    Q: Is it okay to take other supplements along with THINKdrops™?

    A: Yes, take each of our supplements as directed on the label and avoid taking other branded herbal remedies, like caffeine that only mask fatigue and avoid medicinal therapies or prescription drugs like Adderall or Ritalin with THINKdrops™. Consult your health care practitioner if you are under their care.

    Q: Is it safe for kids to take THINKdrops™?

    A: If you are under the age of 18, this product should be taken under the supervision of an adult. All the ingredients in THINKdrops™ are safe for children over the age of 4 years old to take under the guidance of a parent.

    Q: If I suffer with a medical condition, can I take THINKdrops™?

    A: If you are under the care of a licensed practitioner for any condition, please consult with them before taking any dietary supplement.

    Q: When is the best time to take THINKdrops™, and how much should I take?

    A: Spray five pumps directly in your mouth in the morning and five sprays at night. Variance can happen from person to person, adjust the serving size according to your needs. (Some may need only 2-3 sprays, others may need more to achieve the desired results).

    Q: Are the ingredients in THINKdrops™ clinical proven to work?

    A: Yes, there are numerous clinical studies for each of the ingredients in our THINKdrops™ formula which have demonstrated improved focus, memory, concentration, clarity, hearth health, anti-inflammatory, cell membrane, and NRF2 support.

    Q: Are there any adverse reactions or side effects?

    A: There are no known adverse reactions or side effects for the nutrients in THINKdrops™. Discontinue use if you suspect any adverse reaction does occur.

    Q: What makes THINKdrops™ a clean product?

    Answer: THINKdrops™ has been formulated caffeine free, NON-GMO, dairy free, gluten free, Keto friendly, nut free, not tested on animals, made in recyclable bottle.

    Q: Are there any allergens in THINKdrops™?

    A: There are no known adverse reactions or side effects from the nutrients in THINKdrops™. If you are under the age of 18, pregnant, or have a pre-existing medical condition, consult with your healthcare provider before taking this product. Discontinue use if you suspect any adverse reaction does occur.

    1. Michaud, M. M. (2020, August 5). Study Reveals Brain’s Finely Tuned System of Energy Supply. URMC Newsroom. https://www.urmc.rochester.edu/news/story/study-reveals-brains-finely-tuned-system-of-energy-supply

    2. Salim, S. (2016). Oxidative Stress and the Central Nervous System. Journal of Pharmacology and Experimental Therapeutics, 360(1), 201–205. https://jpet.aspetjournals.org/content/360/1/201

    3. Mary Ellen Ellis. “Turmeric and Other Anti-Inflammatory Spices.” Healthline, Healthline Media, 9 Oct. 2013, www.healthline.com/health/osteoarthritis/turmeric-and-anti-inflammatory-herbs.

    4. Sharifi-Rad, Javad et al. “Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications.” Frontiers in pharmacology vol. 11 01021. 15 Sep. 2020, doi:10.3389/fphar.2020.01021 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522354/

    5. Radbakhsh, Shabnam et al. “The effects of curcumin on Brain-Derived Neurotrophic Factor expression in neurodegenerative disorders.” Current medicinal chemistry, 10.2174/0929867330666230602145817. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571425/

    6. Wong, K. H., Naidu, M., David, R. P., Bakar, R., & Sabaratnam, V. (2012). Neuroregenerative potential of lion's mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (higher Basidiomycetes), in the treatment of peripheral nerve injury (review). International journal of medicinal mushrooms, 14(5), 427–446. https://www.dl.begellhouse.com/journals/708ae68d64b17c52,03ea8c440cfbb276,23c2fd3840f4e0c9.html

    7. Chong, P. S., Fung, M. L., Wong, K. H., & Lim, L. W. (2019). Therapeutic Potential of Hericium Erinaceus for Depressive Disorder. International journal of molecular sciences, 21(1), 163. https://www.mdpi.com/1422-0067/21/1/163

    8. Green, K. N., Steffan, J. S., Martinez-Coria, H., Sun, X., Schreiber, S. S., Thompson, L. M., & LaFerla, F. M. (2008). Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. The Journal of neuroscience: the official journal of the Society for Neuroscience, 28(45), 11500–11510. https://www.jneurosci.org/content/28/45/11500

    9. Liu, D., Pitta, M., Jiang, H., Lee, J. H., Zhang, G., Chen, X., Kawamoto, E. M., & Mattson, M. P. (2013). Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession. Neurobiology of aging, 34(6), 1564–1580. https://www.sciencedirect.com/science/article/abs/pii/S0197458012005970?via%3Dihub

    10. Turunc Bayrakdar, E., Uyanikgil, Y., Kanit, L., Koylu, E., & Yalcin, A. (2014). Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1-42)-induced rat model of Alzheimer's disease. Free radical research, 48(2), 146–158. https://www.tandfonline.com/doi/full/10.3109/10715762.2013.857018

    11. Liu, D., Pitta, M., & Mattson, M. P. (2008). Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction. Annals of the New York Academy of Sciences, 1147, 275–282. https://nyaspubs.onlinelibrary.wiley.com/doi/10.1196/annals.1427.028

    12. Glade, M. J., & Smith, K. (2015). Phosphatidylserine and the human brain. Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781–786. https://www.sciencedirect.com/science/article/abs/pii/S0899900714004523?via%3Dihub

    13. Vakhapova, V., Cohen, T., Richter, Y., Herzog, Y., Kam, Y., & Korczyn, A. D. (2014). Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dementia and geriatric cognitive disorders, 38(1-2), 39–45. https://www.karger.com/Article/FullText/357793

    14. Kim, H. Y., Akbar, M., & Kim, Y. S. (2010). Phosphatidylserine-dependent neuroprotective signaling promoted by docosahexaenoic acid. Prostaglandins, leukotrienes, and essential fatty acids, 82(4-6), 165–172. https://doi.org/10.1016/j.plefa.2010.02.025

    15. Karuppagounder, S. S., Pinto, J. T., Xu, H., Chen, H. L., Beal, M. F., & Gibson, G. E. (2009). Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochemistry international, 54(2), 111–118. https://doi.org/10.1016/j.neuint.2008.10.008

    16. 16. Prasad, K. N. (2014). Etiology of Parkinson’s Disease: Prevention and Improved Management by Micronutrients. In Neurodegenerative Disease and Micronutrients (1st Edition). Boca Raton, FL: CRC Press. https://doi.org/10.1201/b17497

    17. Matthews, R. T., Yang, L., Browne, S., Baik, M., & Beal, M. F. (1998). Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proceedings of the National Academy of Sciences, 95(15), 8892–8897. https://www.pnas.org/doi/full/10.1073/pnas.95.15.8892

    18. Barcelos, I. P., & Haas, R. H. (2019). CoQ10 and Aging. Biology, 8(2), 28. https://www.mdpi.com/2079-7737/8/2/28

    19. Gu, Jiachen et al. “Neuroprotective Effect of Trans-Resveratrol in Mild to Moderate Alzheimer Disease: A Randomized, Double-Blind Trial.” Neurology and therapy vol. 10,2 (2021): 905-917. doi:10.1007/s40120-021-00271-2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571425/

 
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